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151,152 GDH1 depletion results in imbalanced redox homeostasis and cell cytotoxicity and attenuates cancer cell proliferation, which as well as the results in erythroleukemia cells, while it negligibly affects normal cell proliferation

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This cascade may possibly lead to the proliferation, survival, migration, and differentiation of endothelial cells, which are posited to be the building blocks of new blood vessels