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[64] In the ALLHAT trial, although serum cholesterol levels were slightly higher after 4 years in chlorthalidone-treated patients than in those treated with amlodipine or lisinopril (197 mg/dl for chlorthalidone vs

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The beneficial effect may be attributed to CUR’s ability to inhibit superoxide production by macrophages, suppress inflammatory factors, modulate NF-κB signaling, and reduce lipid peroxidation