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By directly comparing the cellular uptake of anti-FITC-594 mediated by 50 nM Ab-FA and 200 nM FA-FITC, a significantly greater amount of internalized anti-FITC-594 was observed in the cells treated with Ab-FA than FA-FITC, suggesting that antibody-based degrader Ab-FA has higher uptake efficiency over FA-FITC (Fig

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Interestingly, children with intellectual disability have significantly lower serum levels of SELENOP (Gorlich et al., 2022), suggesting that the transport protein plays an essential role in proper brain development