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Phase 2 trial data published in 2023 in the New England Journal of Medicine (Jastreboff et al., NEJM 2023) reported mean weight reductions of up to approximately 24% over 48 weeks in adults with obesity — notably higher than results seen with currently approved agents
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Effect of high-fat diet feeding on GSH, 25(OH)VD, and carbonyl protein levels in blood, and GSH metabolism genes and VD regulatory genes in liver and muscle in mice Male C57BL/6J mice (5 weeks old) were purchased from The Jackson Laboratory (Bar Harbor, ME)
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