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In nrf2aΔ5 homozygous mutants, the expression of tsh- β was greatly increased compared with their WT siblings (Fig 2S, second from the left), consistent with the known effects of a lack of T.H

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The Somatomedin hypothesis states that postnatal growth that is induced by GH is mediated by hepatic IGF-1 (previously known as Somatomedin C or sulfation factor) in an endocrine manner (156)