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Our understanding of the humoral and neuronal systems that mediate the control of energy homeostasis has improved dramatically in the past few decades

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Oral, intravenous, and inhalation studies The LD 50 s for ethylene oxide, administered orally and dissolved in water, were 330 mg/kg body weight for male rats and 280 and 365 mg/kg body weight for female and male mice, respectively (Smyth et al., 1941