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Insuffisance rénale sévère : les patients dont le débit de filtration glomérulaire est très bas doivent être surveillés, car leur capacité à éliminer l'excès de vitamine hydrosoluble est compromise, ce qui augmente le risque d'accumulation plasmatique

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When to Consider Oral Vitamin B12 Supplements For Maintenance or Mild Deficiency : If you’re generally healthy and need B12 supplementation to maintain healthy levels or correct a mild deficiency, oral supplements are a convenient and cost-effective option