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It also plays crucial roles in the immune response, DNA repair, mitochondrial function and the detoxification of drugs, chemicals, heavy metals, radiation, metabolic wastes, and other toxins and carcinogens

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Dans des adipocytes en culture, les inhibiteurs de NNMT ont réduit le 1-méthylnicotinamide intracellulaire, augmenté le NAD+ et la S-adénosylméthionine, et supprimé la lipogenèse [2]