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Drug delivery and therapy The intracellular redox potential of the glutathione/glutathione disulfide (GSH/GSSG) couple in mammalian cells typically ranges between − 2260 mV and − 200 mV, which is significantly more negative than the extracellular environment (approximately − 140 mV) Fig

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Two years after albiglutide (Tanzeum), approval of a FIX albumin fusion, albutrepenonacog alfa (Idelvion), for treatment of hemophilia B, followed 80