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CCL2 , IL10 , IL1RA , and IL6 were not differentially expressed when impaired and non-impaired individuals were compared, and these genes did not respond to incubation with B12 (Additional file 4)

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Ribbons tether synaptic vesicles and calcium channels and have been hypothesized to play important roles in the facilitation of synaptic vesicle release within the synaptic vesicle cycle in a calcium-dependent manner, with vesicles being released when calcium channels are opened [69,71,72,73,74,75,76,77]