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Measurement of serum TSH, fT3 and fT4 Blood collected from the tail vein of the rats was chilled on 4 °C overnight and then spun at 6000 g for 10 min before collection of the serum

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Hinge like the angiotensin IV antagonist Norleual, was established as a c-Met antagonist by its ability to block HGF-dependent c-Met phosphorylation and prevent HGF-dependent scattering in the MDCK epithelial cell line