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To characterize oxygen gradients within the microdevice, a fluorescence-based oxygen sensor was embedded, composed of silica microparticles loaded with Ru (Ph 2 phen 3 ) Cl 2 (oxygen-sensitive) and Nile blue chloride (oxygen-insensitive control)

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TB-500, a synthesized fragment, mirrors many of TB4's systemic repair properties and is known to distribute broadly throughout the body, supporting healing across multiple tissue types simultaneously