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Inducers of CYP3A4 The concomitant use of Hydrocodone Bitartrate and Acetaminophen Tablets and CYP3A4 inducers, such as rifampin, carbamazepine, and phenytoin, can decrease the plasma concentration of Hydrocodone Bitartrate and Acetaminophen Tablets [see CLINICAL PHARMACOLOGY], resulting in decreased efficacy or onset of a withdrawal syndrome in patients who have developed physical dependence to Hydrocodone Bitartrate and Acetaminophen Tablets [see WARNINGS]

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Multivariate Data Analysis All the obtained time domain NMR data were Fourier transformed, phase corrected, and baseline corrected manually