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Huang and colleagues found that lovastatin induces mitochondrial oxidative stress in human CRC cells, resulting in the cytoplasmic release of mtDNA, which triggers the cGAS-STING signaling pathway in HCT116 cells, ultimately inducing apoptosis and inhibiting the growth and proliferation of CRC cells (146)
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Different oxidation states of cysteine exhibit distinct reactivity and act as redox switches to regulate protein functions [102]
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