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In the withdrawal trial, participants switched to placebo regained about 14% over the following year.¹² Tapering, at least 1.2 g/kg of protein, resistance training, and follow-up reduce the risk, but no post-stop protocol guarantees maintenance
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Note that compound 90 mainly binds to sites 14–15 (the doorstop pocket) while its occupancy in site 5 is low
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