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As a result of the inability to synthesise the vitamin endogenously, ascorbate requiring animals express intestinal sodium‐dependent ascorbate transporters (SVCT1) to actively uptake the vitamin from the diet [4]

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On the other hand, when there are not enough nutrients available to support this anabolic process, AMP-activated kinase (AMPK) is activated to inhibit anabolism and promote the catabolic process to restore ATP levels in the cells [74]