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[DOI] [PMC free article] [PubMed] [Google Scholar] 37.Menchini R.J., Chaudhry F.A

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ROS-generated free radicals cause lipid peroxidation, DNA fragmentation, cell death, DNA damage, protein structure alteration, and membrane degradation.3 This oxidative stress is involved not only in the toxicity of xenobiotics, but also in the pathophysiology of a variety of diseases such as cancer, ischemia-reperfusion injury, vascular endothelium, cardiovascular diseases, deep injuries, inflammation, sepsis, diabetic retinopathy, and organ dysfunction.3 ROS is produced during physiological cell functions such as aerobic respiration or inflammatory responses