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In addition, ferroptosis is positively or negatively regulated by several transcription factors, including nuclear factor E2-related factor 2 (NRF2), activating transcription factor 3/4 (ATF3/4), Yes-associated protein 1 (YAP1), and hypoxia-inducible factor lα (HIF1A) (28)

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Researchers use GHK-Cu as a copper-binding peptide model for studying peptide signaling, gene expression, and extracellular-matrix-related pathways