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The drug once absorbed by intestinal cells enters the portal vein by the passive diffusion, whereas its glucuronides formed in the intestinal cell excrete on the basolateral side (gut lumen) by the efflux transporters

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The GATA1 primer sequences were described previously.27 USP7 primer sequences were: forward: 5’-AGCGTGGCATCACCATAATC-3’ and reverse: 5’-CGAGGCAACCTTTCAGTTCA-3’

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