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Cognitive decline and Alzheimer’s disease Alzheimer’s disease (AD) is a form of dementia characterized by extracellular deposition of β-amyloid plaques, intracellular formation of neurofibrillary tangles, and neuronal loss, eventually leading to brain atrophy and cognitive impairment in affected individuals (57)
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(B) In the presence of mitochondria and NADH, NR decreased DCF fluorescence at a concentration of 1 µM and increased DCF fluorescence at a concentration of 10 µM
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