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The top 500 protein hits from the fitted model (nondirectional set) as well as the top 200 positive hits and the top 200 negative hits (directional sets), in all cases ordered by statistical significance, were used to explore enrichment of functional annotations

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Interestingly, we found that DSS injury, much like OSKM reprogramming, was associated with a significant depletion of serum vitamin B 12 levels (Fig