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Abstract Diabetes mellitus (DM) is a complex metabolic disorder arising from lack of insulin production or insulin resistance (Diagnosis and classification of diabetes mellitus, Introduction In mammalian cells, under normoglycemia (3.8–6.1 mmol/L), cellular glucose is predominantly phosphorylated into glucose 6-phosphate by hexokinase, and enters the glycolytic pathway

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In the case of GM the authors point out that restricting carbohydrates would likely make the glutamine effective in an anti-GM biology