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Collectively, GGCT functions as a metabolic rheostat that orchestrates mitochondrial homeostasis through diverting Gln flux toward glutathione biosynthesis to fortify redox defense, while enhancing Glc-fueled TCA cycle anaplerosis to sustain cell proliferation

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GST and Detoxification Research Provides glutathione conjugates and related derivatives for GST substrate evaluation, inhibition studies, and pathway-focused mechanistic work