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In this relatively recent description syndrome of FCM, at least in its complete form, the absorption of unbound (“free” or crystalline) cobalamin remains normal (Figure 1) [8]

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The effectiveness of hydroxocobalamin was examined in a randomized, placebo-controlled, blinded study in cyanide-poisoned adult dogs assigned to treatment with vehicle (0.9% saline), or 75 or 150 mg/kg hydroxocobalamin