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In contrast, accumulating evidence indicates that a subset of TNBC tumors and cell lines display significant mitochondrial respiration, enhanced tricarboxylic acid (TCA) cycle activity, and sensitivity to OXPHOS inhibition

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In catalase-deficient barley ( Hordeum vulgare ) and tobacco, however, oxidative perturbation of glutathione (accumulation of GSSG to many-fold wild-type levels) precedes or accompanies the appearance of lesions (Smith et al., 1985