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ii) the CRH neurons of the paragigantocellular and parabranchial nuclei of the medulla and (iii) the noradrenergic nuclei of the medulla and pons, including the locus caeruleus (LC), regulating arousal, and other nuclei mostly secreting norepinephrine (NE) and regulating the systemic sympathetic and adrenomedullary, as well as the parasympathetic nervous systems
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A product of lipid peroxidation, 4-hydroxynonenal, has been shown to induce apoptosis in neuroblastoma cells by elevating the levels of p53, p63 and p73 and p63 staining has been used as a marker for prostatic adenocarcinoma where lack of p63 staining indicates malignant prostatic adenocarcinoma [14,18]