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M.GuimarãesJ

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The reduced glutathione levels might occur partly due to the redirection of L-cysteine into the pathway for the synthesis of sulfane sulfur-containing compounds, as evidenced by the observed increase in expression levels for the CTH gene in the WT (Figure 4A,C) and Naglu −/− (Figure 4A) cell lines and in CTH activity (the WT cells, Figure 5B,C)