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Randomized blinded trials became the gold standard for clinical trials in the mid-twentieth century

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Impact of glycine supplementation on glutathione and markers of oxidative stress (glycine feeding study) Forty-four senior cats (twenty-eight female, sixteen male), of which thirty-nine participated in the GLY inclusion level study, with a median age of 11·7 years (range 7·7–13·8 years), took part in the 16-week study, comprising a 4-week acclimation phase and a 12-week test phase (Fig