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Associations between telomere length and cardiometabolic dysregulation Given that telomere shortening may be a risk factor for age-related pathology including metabolic dysregulation 55,56,57 and cardiovascular disease 16,18,58,59,60 , we examined associations between TL and markers of insulin resistance (Triglyceride-Glucose index [TyG index]) as well as a marker of cardiovascular risk (cardiometabolic risk [CR] score 61 )

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