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Anti-VEGFR2 antibody blockade abolishes these effects, confirming receptor-mediated rather than VEGF-ligand-independent angiogenesis

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Animals were then dosed intravenously via the jugular vein catheters, with D-Nle-Tyr-Ile-NH—(CH 2 ) 5 —CONH 2 (24 mg/kg) in 30% ethanol

looking skin by minimizing fine lines and improving texture