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ICD-10-CM Code D51.0 Definition and Clinical Description The CDC ICD-10-CM web tool defines D51.0 as “Vitamin B12 deficiency anemia due to intrinsic factor deficiency.” This medical classification captures a specific pathophysiology: autoimmune destruction of gastric parietal cells reduces intrinsic factor production, which prevents B12 binding and absorption in the terminal ileum

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They recur with each injection, sometimes for weeks or months before improving