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Ochronosis can occur through the prolonged usage of hydroquinone in the absence of sufficient photoprotection (Bronzina et al., 2020)

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longa L., rhizoma, as herbal medicinal product in the form of powdered herbal substance, comminuted herbal substance, dry extract [13–25:1, extraction solvent: ethanol 96% (v/v)], dry extract [5.5–6.5:1, extraction solvent: ethanol 50% (v/v)] and tinctures (1:5 or 1:10, extraction solvent: ethanol 70% (v/v)