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In agreement with this, USP2 OE enhanced the protein level of TGFBR1 and phospho-SMAD3 (pSMAD3), and the expression of COL1A1 , COL1A2 , SERPINE1 , and SMAD7 , the prototypic TGFβ signaling target genes, under TGFβ1 stimulation (Fig
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