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The procedure involves: Identifying one or more trigger points in one or two muscles Sterilizing the injection site Inserting a needle into the taut muscle band Injecting medication to relieve pain, reduce inflammation, and improve function These injections may be performed for a variety of clinical conditions, including myofascial pain syndrome, fibromyalgia, neck and back pain, and sports-related muscular tightness
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Most improvements of therapy (e.g., alpha-agonists) aim to selectively (eg, sub-type-selective alpha1-adrenoceptor agonists) affect urethral pressure, peripherally [5], and most recently, centrally [6], and these therapies may affect the bladder or urethral properties of healthy subjects (e.g., selective, partial agonist at the human alpha1(A)-adrenoceptor) [6], explaining the elevation in leak point pressure (LPP)
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