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Identification of immunogenic HLA-DR–presented self-peptides from synovial tissue Because of the large number of PBMCs required to test T cell reactivity of 30 candidate peptides in large numbers of patients as well as the need to conserve cells for other subsequent analyses, we selected only certain peptides of interest for detailed analysis

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These methods are mainly aimed at inhibiting or reducing the abnormal proliferation of tumor cells, many of them by inducing ROS that trigger DNA damage and cell death [143]