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Melanin synthesis is first slowed by glutathione’s direct inhibition of tyrosinase activity
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Animal studies have shown that low levels of GSH downregulate the VD-regulatory (VDBP/VD-25-hydroxylase/VDR) and glucose-metabolism (PGC-1α/VDR/GLUT-4) genes in the liver, kidney, and muscle of HFD-fed mice and diabetic rats [56,58,73,81]
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