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NAD+ Restoration (Anti-Aging): NNMT works by methylating nicotinamide, which removes it from the “NAD+ salvage pathway.” By blocking NNMT, 5-Amino-1MQ preserves nicotinamide, allowing the cell to recycle it back into NAD+ (Nicotinamide Adenine Dinucleotide)

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Since GHRP2 enhances ‘feed forward’ by activating GHRH neurons from outside the main axis, and thereby opposes age-associated degradation of regulatory control within the GH neuroendocrine axis, it is a logical consideration for GHRT by practitioners of anti-aging medicine