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(2015) in patients with mild to moderately active ulcerative colitis, using 5-aminosalicylic acid (5-ASA) at an optimized dose, demonstrated that curcumin supplementation (3 g/day) for 4 weeks improved clinical response and induced remission in patients with ulcerative colitis, but did not affect CRP and hemoglobin levels

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When an increase occurs as in the case of the humans living in polluted areas or exposed to pesticides [183]