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This happens for several reasons: Caloric deficit magnitude: The dramatic appetite suppression from semaglutide creates substantial caloric deficits
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We observed that plasma and muscle glutamine concentrations fell steadily throughout lactation in the horse and this was accompanied by a loss of skeletal muscle, representing a mildly catabolic state (Manso Filho et al., 2008) as seen in a number of other species (Manso et al., 2012, Clowes et al., 2005, Pine et al., 1994)
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