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There are also other studies indicating that some drugs exert anti-RA effects by regulating PI3K/AKT and MAPK signaling pathways (Wang et al., 2023

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Future efforts should focus on developing novel imaging probes or methodologies, such as PET tracers or functional MRI techniques targeting active lipid peroxides, redox imbalance, or ferroptosis-specific membrane damage, to enable quantitative and localized analysis of ferroptosis in the living human brain