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Prednisone is then tapered to a single every other day dose by gradually reducing an alternate "off-day" dose by 10 mg per week, or faster if necessitated by side effects

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Keywords: Bile acid transporters, Genetic susceptibility, Inflammation, Mitochondrial dysfunction, Oxidative stress, Personalized medicine, SLCO1B1 polymorphisms Methodology This narrative review employed a structured literature search to examine the molecular mechanisms, clinical implications, and management strategies associated with atorvastatin-induced hepatotoxicity, synthesizing findings from studies published between 2000 and 2025