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As Figure 6 shows, just as in the case of oligomers preincubated for 48 h in the presence of Semax or Semax-Cu(II) and then added to the d-SH-SY5Y cells, the Semax in this case also protects the cells from the toxicity of the already pre-formed oligomers, reducing Aβ 1–42 -induced cell toxicity by up to 90% in both the case with and that without copper