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Likewise, Erfe splenic mRNA expression was increased, particularly when Gpx4 deletion and vitamin E-deficiency were combined
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‘Back-side’ nucleophilic attack by glutamate ion Glu540 (or Glu504 in bacterial ortholog) – the catalytic nucleophile, stabilizes the transition state and results in glucuronyl ester intermediate ( 3 ) with an inverted configuration
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