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Available from: 20.Novo Nordisk starts phase 1 trial with long-acting oral GLP-1 analogue (13 Jan 2010) Available from: 21.Dakin CL, Small CJ, Batterham RL, Neary NM, Cohen MA, Patterson M, Ghatei MA, Bloom SR

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Fumarate itself is a Michael acceptor, and the covalent attachment to protein cysteines corresponds to the post-translational modification known as succination [142] and fumarate has been recently demonstrated to yield a glutathione thioether in in vitro treated cells [142]