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Recently, neural activity mediated by NMDA-receptors (NMDAR) has been coupled with transcriptional activation of glutamate-cysteine ligase, a key enzyme in GSH production, leading to a sustained GSH-based protection against an oxidative insult 26

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[12] Lastly, ALA may have mild anticoagulant effects (by enhancing blood flow and endothelial function), so combining it with anticoagulant or antiplatelet drugs could very slightly increase bleeding tendency

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