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(2024) SARS-CoV-2 virulence factor ORF3a blocks lysosome function by modulating TBC1D5-dependent Rab7 GTPase cycle
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During ischemia, oxygen deprivation forces cells to rely on anaerobic metabolism, resulting in ATP depletion and impaired function of ion pumps such as Na⁺/K⁺-ATPase, leading to ionic imbalances [7]
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