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Furthermore, the same test subjects failed to respond when MSG was given with food.¹⁷ ²⁷ A systematic review of over 60 studies that purported to examine the effects of MSG ingestion on asthma failed to demonstrate a link, however only two studies met the reviewers’ rigorous inclusion criteria.³² A recent placebo-controlled study of individuals who self-reported an irregular heartbeat, atrial fibrillation (AF), in association with MSG consumption, demonstrated no association between AF and doses of 3 g of MSG.³¹ Bottom line: There is no reproducible scientific evidence that the general population or even self-identified MSG-sensitive individuals, are adversely affected by ingestion of MSG with food or on an empty stomach