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In the last 20 years, the number of IPR and DPR projects employing membrane technologies has increased significantly in the U.S., Australia, Singapore, and South Africa (Table 1)

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At doses of 25, 50, and 100 mg/kg per day, SZ was reported to induce analgesic effects in an animal model of inflammatory pain, while in the same study a dose of 8 mg/kg per day showed no effects (Bernabucci et al., 2019)