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[35] In 1931, the American Chemical Society awarded Pauling the Langmuir Prize for the most significant work in pure science by a person 30 years of age or younger

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Specifically, IL-5 priming led Siglec-8 cross-linking to cause a loss of mitochondrial membrane potential and production of ROS inside the eosinophil, which in turn drove the cell into apoptosis through a caspase-independent mechanism (183)