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Ipilimumab was the first CTLA-4-blocking antibody approved by the US FDA for the treatment of human cancers

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doi: 10.3389/fncel.2019.00172 Received 20 July 2018 Accepted 11 April 2019 Published 30 April 2019 Volume 13 - 2019 Edited by Antonio Gambardella, Università degli Studi “Magna Græcia” di Catanzaro, Italy Reviewed by Ursula Susan Sandau, Oregon Health & Science University, United States